2012年5月29日星期二

What's We Know About Aesculetin




Product name:Aesculetin
CAS:305-01-1
Molecular Formula:C9H6O4
Molecular Weight: 178.14g/mol
Description of Aesculetin:
Aesculetin (also known as esculetin, 6,7-dihydroxycoumarin and cichorigenin) is a derivative of coumarin. It is a natural lactone that derives from the intramolecular cyclization of a cinnamic acid derivative.
It is present in many toxic and medicinal plants, in form of glycosides and caffeic acid conjugates.
Esculetin-containing preparations used systemically can have an anticoagulant effect and might interact with anticoagulent drugs such as warfarin.
This compound is used in some sunscreens, but there is evidence that it acts as a photosensitizer for DNA damage.The sodium salt of its methyl-derivative is used in dermatology for the treatment of varicose veins.
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  1. Esculetin isolated from the peel of Aesculus hippocastanum L. It can quench the inner fluorescence of bovine serum albumin. Esculetin

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