What's We Know About Brucine

Product name:Brucine
CAS:357-57-3
Molecular Formula:C23H26N2O4
Molecular Weight: 394.46g/mol
Description of Brucine:
Synonyms:Strychnidin-10-one, 2,3-dimethoxy-;(-)-Brucine;Brucine alkaloid;Brucin;Brucina;Dimethoxy strychnine;2,3-Dimethoxy-strychnine;10,11-Dimethystrychnine;Rcra waste number P018;Strychnine, 2,3-dimethoxy-;UN 1570;10,11-Dimethoxystrychnine;2,3-Dimethoxystrychnidine-10-one;2,3-Dimethoxystrychnidin-10-one
Appearance:  white crystalline powder
Melting Point:  177 C
Water Solubility:  slight
Stability:  Stable. Combustible. Incompatible with strong oxidizing agents.
Brucine is a bitter alkaloid closely related to strychnine. It occurs in several plant species, the most well known being the Strychnos nux-vomica tree, found in South-East Asia.
While brucine is related to strychnine, it is not as poisonous. Nevertheless, a human consuming over 2 mg of pure brucine will almost certainly suffer symptoms resembling strychnine poisoning (LD50 (rats, oral) 1 mg/kg, LD50 (rabbit, oral) 4 mg/kg). The probable fatal dose in adults is estimated at 1 gram.Another source gives the minimal lethal dose in humans as 30 mg.
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