2012年4月26日星期四

Oridonin Manufacturer from China




Product name:Oridonin
CAS:28957-04-2
Molecular Formula:C20H28O6
Molecular Weight: 364.43g/mol
Description of Oridonin:
A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative (ED50 ~ 2.7 µg/ml in lymphoid malignant cells) and antiangiogenic properties (significantly inhibits network formation of HMEC-1 cells at 2.5 µg/ml). Reported to affect DNA synthesis, induce apoptosis and initiate cell cycle arrest. Shown to efficiently block both TNF-α and LPS-induced NF-κB activity in Jurkat and in RAW264.7 murine macrophages, and inhibit p65 NF-κB transcriptional activity (IC50 ~ 5 µg/ml in MT-1 cells) by disrupting NF-κB DNA-binding activity without interfering with its nuclear translocation.
Handling: Protect from air and moisture
USAGE: For Research Use Only! Not For Use in Humans.
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Health Benefits of Scopoletin




Product name:Scopoletin
CAS:92-61-5
Molecular Formula:C10H8O4
Molecular Weight: 192.17g/mol
Description of Scopoletin:
Synonyms:7-Hydroxy-6-methoxycoumarin, gelseminic acid, chrysatropic acid, esculetin-6-methyl ether
Pure scopoletin is a yellow to beige crystalline powder. Scopoletin belongs to the group of coumarins.
Health Benefits of Scopoletin:
Scopoletin seems to regulate the blood pressure: when the blood pressure is high, scopoletin helps to lower it and when it is too low it can help raise it.
Scopoletin has bacteriostatic activity against various species of bacteria, including Escherichia coli, Staphylococcus aureus, Streptococcus sp., Klebsiella pneumoniae and Pseudomonas aeruginosa.
Scopoletin has anti-inflammatory activity and can be used to treat bronchial illnesses and asthma. Scopoletin regulates the hormone serotonin, which helps to reduce anxiety and depression.
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Chemical Properties of Indirubin




Product name:Indirubin
CAS:479-41-4
Molecular Formula:C16H10N2O2
Molecular Weight: 262.26g/mol
Description of Indirubin:
Synonym: Isoindogotin
Derived from: Synthetic
Physical Appearance: Dark Purple solid
Solubility: DMSO (10mg/ml) and methanol (0.3mg/ml). Sparingly soluble in aqueous buffers (12.5µg/ml).
Melting Point: 332-340℃
Purity:98%min
Storage:Store at 4° C
It is active pharmaceutical ingredient.
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Hot Sale Indigo




Product name:Indigo
CAS:482-89-3
Molecular Formula:C16H10N2O2
Molecular Weight: 262.26g/mol
Description of Indigo:
EINECS: 207-586-9
Synonyms: Indigotin;Indigo natural;Indigo,CI 73000 synthetic;Indigo,CI 73000;Indigotin,CI 73000;3H-Indol-3-one, 2-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro-;«delta»2,2'-Bipseudoindoxyl;(«delta»2,2'(3H,3'H)-Biindole)-3,3'-dione;(«delta»2,2'-Biindoline)-3,3'-dione;Blue No. 201;C.I. 73000;Cystoceva;D And C Blue No. 6;D And C Blue Number 6;D+C Blue No. 6;D&C Blue No.6;D&C Blue 6;Diindogen;Indigo blue;
Appearance: Dark blue to violet to purple powder
Melting Point: > 300℃
Stability: Stable. Incompatible with strong oxidizing agents.
Storage:Store at room temperature
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Best Provider of Lobetyolin




Product name:Lobetyolin
CAS:136085-37-5
Molecular Formula:C20H28O8
Molecular Weight:396.43 g/mol
Description of Lobetyolin:
IUPAC Name: 2-(1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol
Synonyms:(7E)-2-Hydroxy-1-[(1E)-5-hydroxy-1-penten-1-yl]-7-nonene-3,5-diyn-1-yl b-D-glucopyranoside
Appearance:yellow powder
Purity:98%min
Test Method:PHLC
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2012年4月12日星期四

Formononetin at Competitive Price




Product name:Formononetin
CAS:485-72-3
Molecular Formula:C15H10O4
Molecular Weight: 254.24g/mol
Description of Formononetin:
Formononetin is a phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the g-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
Storage:Protect from light. Packaged under inert gas.
Solubility:DMSO ≥54mg/mL; Water <1mg/mL;Ethanol <1mg/mL
Stability:at -20℃ 2 years
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China Irisflorentin Supplier




Product name:Irisflorentin
CAS:41743-73-1
Molecular Formula:C20H18O8
Molecular Weight: 386.35g/mol
Description of Irisflorentin:
Synonyms: 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one
Purity:≥98%
Specification: 20mg
High purity,good quality and very competitive price
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Best Supplier of Andrographalide




Product name:Andrographalide
CAS:5508-58-7
Molecular Formula:C20H30O5
Molecular Weight: 350.45g/mol
Description of Andrographalide:
IUPAC name:3-[2-[decahydro-6-hydroxy-5- (hydroxymethyl)-5,8a- dimethyl-2-methylene-1- napthalenyl]ethylidene]dihydro- 4-hydroxy-2(3H)-furanone
Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Andrographolide is an extremely bitter substance extracted from the stem and leaves of the andrographis paniculata, which is grown for medicinal purposes in China and India.
Melting point: 229-232 ºC
Alpha: -126 º (c=1.5,HAc)
Form: Off-white solid
Purity:≥98%
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Hot Sale Nobiletin




Product name:Nobiletin
CAS:520-26-3
Molecular Formula:C28H34O15
Molecular Weight: 610.56g/mol
Description of Nobiletin:
Synonyms:3',4',5,6,7,8-hexamethoxyflavone
Nobiletin is a citrus flavonoids with a structure similar to that of tangeretin. It has the typical flavonoid structure and contains 6 methoxyl groups, one more than tangeretin. This high level of methoxylation increases the hydrophobic character of tangeretin. Pure nobiletin has the appearance of colorless needles and has a bitter taste.
Distribution:Peels of citrus fruits.
Appearance:colorless crystal
Melting point:137-138℃
Purity:≥98%
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Health Benefits of Hespiridin





Product name:Hespiridin
CAS:520-26-3
Molecular Formula:C28H34O15
Molecular Weight: 610.56g/mol
Description of Hespiridin:
Health Benefits of Hesperidin
Hesperidin has antioxidant, anti-inflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions. Hesperdin can inhibit following enzymes: phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase.
Hesperidin improves the health of capillaries by reducing the capillary permeability.
Hesperidin is used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. The possible anti-cancer activity of hesperidin could be explained by the inhibition of polyamine synthesis.
A study showed that hesperidin added to the died not only lowered serum and hepatic cholesterol, but also inhibited bone loss by decreasing osteoclast number in ovariectomized mice. The molecular mechanism of the inhibitory effect of hesperidin on bone resorption is not clear.
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2012年4月10日星期二

Function of Menthol

Product name:Menthol
CAS
:15356-70-4
Molecular Formula:C10H20O
Molecular Weight: 156.27g/mol
Description of Menthol:
Menthol is an organic compound naturally occurring in mint plants. It is also synthetically manufactured. Menthol is widely used in a number of products and features certain therapeutic qualities. It was first isolated from peppermint oil in 1771 in the West, but it may have been in use in Japan for much longer.
Most of menthol's uses are related to its stimulation of the skin's cold receptors. This property makes Menthol produce a cooling effect when inhaled or applied to the skin. Similarly to the capsaicin chemical found in hot peppers, which stimulates heat receptors, menthol does not actually change the skin's temperature, but merely produces the sensation of temperature change.
Because of its cooling effect, menthol is used in products meant to relieve skin irritation, sore throat, or nasal congestion. It may be used to treat sunburn, fever, or muscle aches as well. In traditional Asian medicine, menthol may be prescribed for nausea, diarrhea, indigestion, headache, cold, or sore throat. When used as a supplement for health reasons, menthol is usually taken in the form of peppermint oil. Products that commonly contain menthol include toothpaste, cough drops, lip balm, mouthwash, gum, and cigarettes.
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Sell Peiminine at Competitive Price



Product name:Peiminine
CAS:
18059-10-4
Molecular Formula:C27H43NO3
Molecular Weight:429.64 g/mol
Description of Peiminine:
Synonyms:sipeimine, Fritillarine, Imperialine, Zhebeinone, Peiminine, Ambap927, 3beta,20-Dihydroxy-5alpha-cevan-6-one, Cevan-6-one, 3,20-dihydroxy-, (3beta,5alpha)-
Appearance: white powder
Purity:98%
Origin:fritillaria thunbergii mig
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Sell Good Quality Cantharidin


Product name:Cantharidin
CAS
:56-25-7
Molecular Formula:C10H12O4
Molecular Weight: 196.2g/mol
Description of Cantharidin:
IUPAC name:2,6-Dimethyl-4,10-dioxatricyclo-decane-3,5-dione
Cantharidin, a type of terpenoid, is a poisonous chemical compound secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. The false blister beetles and cardinal beetles also have cantharidin.
Medical uses:Diluted solutions of Cantharidin can be used as a topical medication to remove warts and tattoos and to treat the small papules of Molluscum contagiosum.
Density:1.41 g/cm³
Melting point: 212 °C
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China Patchoulialcohol Supplier


Product name:Patchoulialcohol
CAS
:C15H26O
Molecular Formula:C15H26O
Molecular Weight:C15H26O g/mol
Description of Patchoulialcohol:
Other names
:Patchouli camphor;(–)-patchoulol;(1R,3R,6S,7S,8S)-patchoulol, patchouli alcohol
Synonyms: [1R-(1alpha,4beta,4aalpha,6beta,8aalpha)]-octahydro-4,8a,9,9-tetramethyl-1,6-methano-1(2H)-naphthol
Purity: 99.9%min
EINECS No.: 227-807-2
Use: used in the synthesis of the chemotherapy drug Taxol
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What is Chrysin



Product name:Chrysin
CAS
:480-40-0
Molecular Formula:C17H14O7
Molecular Weight: 330.29g/mol
Description of Chrysin:
Other names:5,7-dihydroxyflavone, Chrysin, 5,7-dihydroxy-2-phenyl-(9CI), NP-005901, galangin flavanone
Chrysin is a naturally occurring polyphenol found in the passion flower and in the sticky, resinous substance that bees use to build their hives. Specifically, chrysin belongs to a class of polyphenols known as flavonoids. A wide variety of health claims have been made for chrysin, and early studies-- most of them based on in-vitro testing--have been promising. However, more human tests of chrysin's effects will be needed before its medicinal value can be definitively determined
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Information of Chelerythrine



Product name:Chelerythrine
CAS:
3895-92-9
Molecular Formula:C21H18ClNO4
Molecular Weight: 383.82g/mol
Description of Chelerythrine:
Chelerythrine is a potent and specific inhibitor of protein kinase C.
Chelerythrine Chloride Is an isoquinoline alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae. It has been reported to be a potent and selective inhibitor of protein kinase C (IC50=0.66 µM), and an independent activator of MAPK pathways. The compound has been observed to induce apoptosis in HL-60 human promyelocytic leukemia cells. The proposed method of action of apoptotic stimulation is through the inhibition of binding BclXL to Bax or Bad at an IC50=1.5μM. When used in combination with cisplatin (sc-200896) inhibition of cell proliferation of non-small cell lung cancer cells was increased in an additive/synergistic pattern. Also through inhibition of thromboxane formation and phosphoinositide breakdown Chelerythrine Chloride was demonstrated to inhibit rabbit platelet aggregation and release.
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2012年4月5日星期四

Betulic Acid at Promotional Price


Product name:Betulic Acid
CAS:472-15-1
Molecular Formula:C30H48O3
Molecular Weight: 456.7g/mol
Description of Betulic Acid:
IUPAC name:(3β)-3-Hydroxy-lup-20(29)-en-28-oic acid
Betulinic Acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase.It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name.
Melting point:316–318 °C
Storage:Store in a well-closed container at cool and dry place.Protect from strong light/heat,moisture and pest infestation.
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Bilobalide for Promotion


Product name:Bilobalide
CAS
:33570-04-6
Molecular Formula:C19H18O8
Molecular Weight: 374.34g/mol
Description of Bilobalide:
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.
Bilobalide is a main constituent of the terpenoids found in Ginkgo leaves. It also exists in minor amounts in the roots. It is a sesquiterpenoid, i.e. it has a 15-carbon skeleton.
Bilobalide is important for producing several of the effects of Gingko biloba extracts, and it has neuroprotective effects, as well as inducing the liver enzymes CYP3A1 and 1A2,which may be partially responsible for interactions between gingko and other herbal medicines or pharmaceutical drugs. Bilobalide has recently been found to be an antagonist at the GABAA and GABAA-rho receptors. Of GABAA, it may possibly be selective for the subunits predominantly implicated in cognitive and memory functioning such as α1.
Purity:  98%
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Information of Sasarasapogenin



Product name:Sasarasapogenin
CAS
:126-19-2
Description of Sasarasapogenin:
Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.),a family of climbing plants found in subtropical regions. It was one of the first sapogenins to be identified,and the first spirostan steroid to be identified as such. The identification of the spirostan structure, with its ketone spiro acetal functionality, was fundamental in the development of the Marker degradation, which allowed the industrial production of progesterone and other sex hormones from plant steroids.
Sarsasapogenin is unusual in that it has a cis-linkage between rings A and B of the steroid nucleus, as opposed to the more usual trans-linkage found in other saturated steroids. This 5β configuration is biologically significant, as a specific enzyme – sarsasapogenin 3β-glucosyltransferase – is found in several plants for the glycosylation of sarsasapogenin. The (S)-configuration at C-25 is also in contrast to other spirostan sapogenins: the epimer with a (25R)-configuration is known as smilagenin
Appearance: white powder
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Provide Ferulic Acid at Wholesale Price




Product name:Ferulic Acid
CAS:1135-24-6
Molecular Formula:C10H10O4
Molecular Weight: 194.18g/mol
Description of Ferulic Acid:
Ferulic Acid is a hydroxycinnamic acid, a type of organic compound. It is an abundant phenolic phytochemical found in plant cell wall components such as arabinoxylans as covalent side chains. It is related to trans-cinnamic acid. As a component of lignin, ferulic acid is a precursor in the manufacture of other aromatic compounds. The etymology is from Ferula, referring to the giant fennel.
Ferulic Acid is found in the seeds of coffee, apple, artichoke, peanut, and orange, as well as in both seeds and cell walls of commelinid plants (such as rice, wheat, oats, and pineapple). It can be extracted from wheat bran and maize bran using concentrated alkali.
Melting point:168–172 °C
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What is Beta-Amyrin




Product name:Beta-Amyrin
CAS:559-70-6
Molecular Formula:C30H50O
Molecular Weight: 426.72g/mol
Description of Beta-Amyrin:
Synonym Name:beta-Amyrenol; balanophorin; (3beta)-olean-12-en-3-ol; olean-12-en-3-ol, (3beta)-; 12-oleanen-3-beta-ol
Beta-Amyrin is a precursor of Boswellic acid that is obtained by converting the CH3 in 24 to COOH. Ursolic acid has anti elastase activity, and like cholesterol, modulates the membrane fluidity. It prevents UV-B irradiation damages to the skin through prevention of lipid peroxidation and PGE2 release inhibition. Boswellic acid is a strong 5-lipoxigenase inhibitor and it has also anti elastase and anti GAGase properties. Alpha Amyrin has strong anti-inflammatory activity, is a PKA inhibitor as well as a selective protease inhibitor: chymotrypsin is inhibited at an 18-micromolar level.
Purity:98.0% min
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China Supplier of Beta-pinene


Product name:Beta-pinene
CAS:127-91-3
Molecular Formula:C10H16
Molecular Weight:136.23 g/mol
Description of Beta-pinene:
Beta-Pinene (β-pinene) is a colorless liquid, soluble in alcohol, but not water. It has a woody-green pine-like smell. It occurs naturally in rosemary, parsley, dill, basil, yarrow, and rose. It is also a major constituent of hop aroma and flavor.
Density:0.872 g/mL
Synonyms: 6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane; 
(1S,5S)-(-)-2(10)-Pinene; (-)-beta-Pinene; (-)-2(10)-Pinene; L-beta-pinene; (1S)-(-)-beta-Pinene; laevo-beta-Pinene; (1S)-6,6-Dimethyl-2-methylene bicyclo [3.1.1]heptane
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